Departments

Mission

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Our mission is to deliver cutting edge advanced research and to offer high standard medical diagnostic service and training facilities in our specialization.

Vision

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Our vision is to be a referred center in the field of Electron Microscopy for medical research, diagnosis and training at the level of the country and the regional area.

Research Fields

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Our department’s research focuses on ultrastructural studies in basic medical sciences (pathology, haematology, parasitology and microbiology) specifically in gastrointestinal, liver, and urinary system diseases caused by endemic parasitic and infectious agents. Our strategy is tailored to comply with the institute’s vision and mission and to meet the terms of the four main research programs of the Institute as detailed below:

I-                    Morbidity Changes of Endemic Diseases:

The study of ultrastructural changes occurring in tissues (liver, urinary and gastrointestinal tracts) and blood secondary to:

·          Endemic Parasitic infection  

• Endemic infectious diseases
• tumors and  malignancies

            II-             Diagnosis of Endemic Diseases:

·         Ultrastructural study of premalignant and malignant changes

·         Ultrastructural study of micro-organisms intracellularly and in culture

·         Ultrastructural study of endemic parasites to explore the effect of anti-parasitic innovated drugs and the immunological changes due to host immune response

III-   Management of Endemic Diseases:

·         Evaluating the efficacy and toxicity of currently used and newly discovered drugs on the liver, kidney, bone marrow and other important systems in experimental models.

·         Ultrastructural assessment of pathological changes of therapeutic regimens on human body organs.

·         Stem cells as adjuvant therapy in liver diseases

           IV- Control of Endemic Diseases:

·         Evaluation of the efficacy of newly introduced compounds (eg potential vaccines) at the ultrastructural level.

 

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Techniques

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v Running techniques:

v  Conventional techniques for electron microscopy (transmission and scanning electron microscopy).

v  Cryo-electron microscopy.

v  Immunohistochemistry of tissue sections and cells:

·         Immunofluorescence

·         Immunoperoxidase

v  Immunoelectron labeling

v  Innovated agarose cell block technique for processing of cytology samples (innovated by Mansy 2004).

v  Negative staining for microorganisms.

v  Nanoparticles examination.

 

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Services

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v Scope of Services

v  Medical services:

Ultrastructural pathological diagnosis of different types of human specimens (tissue, blood, body fluids and smears) especially specimens from liver, kidney, urinary bladder and muscle sent from TBRI hospital or referred from other hospitals or private clinics. 

•      Medical Fields of Research:

–     Nephropathology:

•      Processing and diagnosing kidney biopsies from patients suffering from;

–     Acute and chronic kidney injuries and renal transplant biopsies.

•      Our Nephropathology in Collaboration with Pathology Department in TBRI is a unique service that serves the following hospitals ;

•      TBRI hospital

–     Kasr EL Ainy Hospital

–     Abo El Riesh, Children Hospital

–     Al Hosien Teaching Hospital

–     Al Zahraa Teaching Hospital

–     Al Fayoum Teaching Hospital

–     Banha Teaching Hospital

 

v  Scientific consultations:

The department performs scientific consultations to internal and external researchers concerning specimen manipulation, processing and diagnosis.

to internal and external researchers concerning processing & examination of biological & industrial specimens for SEM & TEM

 

v  Routine out and in Patient Services.

Ultrastructural examinations of human biopsies, smears and aspirations are performed upon clinician’s request and not on a routine basis.

Training

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v Training Facilities

v  The electron microscopy research department is unique in having an assembly of highly qualified specialized researchers in pathology, hematology and microbiology .

v  The department organizes bi-annual training courses, concerning the techniques used in electron microscopy and its applications in research and diagnosis for university graduates and post graduate candidates. Special training courses are organized for technicians working in this field.

v  The department gives the opportunity of two scholarships every two years for the fulfillment of M.Sc. in the field of ultrastructural pathology, hematology and microbiology.

Publications

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• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
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Projects

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• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
• Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,