Clinical Chemistry Department

About Department

- Implementation of the highest quality techniques and test parameters for early prediction, diagnosis, follow up of highly incident diseases in Egypt (chronic hepatitis C viral infection, hepatocellular carcinoma, GIT diseases, renal diseases, cardiovascular complications of chronic kidney diseases, urological diseases, autoimmune diseases (Crohn’s and ulcerative colitis), cancer bladder, liver and kidney transplantation.
- Implications of molecular techniques in studying the potential role of genetic variants in pathophysiology of different diseases, studying their role in incidence, prediction, diagnosis and prognosis of diseases.
- One of our priorities is providing high quality laboratory services, so we are participating in external quality control program, planning to be accredited with ISO 15189 certificate and GAHAR accreditation.
- Our aim was to bridge the gap between our laboratory and other departments through highlighting who the Clinical Chemistry deptartment is, what it does and how it does it.

Mission

To provide excellence in laboratory services, training and research activities. Control, early diagnosis and treatment of endemic tropical diseases and their complications (hepatocellular carcinoma, cancer bladder, cardiovascular complications of renal diseases). Moreover; pre- & post-operative monitoring of hepatic and renal transplant subjects.
Work on training specialized doctors who are able to conduct advanced scientific research and apply updated modern technologies and national and international medical standards, with an interest in developing the competitiveness of the workforce.
Human capital and the pursuit of community services and contribution to solving national health problems.

Vision

The clinical chemistry department has a goal to be a central laboratory in research and training concerning prediction, diagnosis, therapeutic monitoring, and follow-up of hepatic, colonic, gastrointestinal, renal, and urological diseases. Our core competencies in inspection, verification, testing, and certification are being continuously improved to be best in class; aiming to be one of the most competitive and productive service providers to our customers and to provide innovative, timely, and quality medical laboratory services.
To care for the development of the competitive edge of human resources, serve the community, and share in solving national health problems.

Research Fields

Research fields:

Hepatic diseases
Hepatocellular carcinoma
GIT diseases
Renal diseases
Cardiovascular complications of renal diseases
Urological diseases
Cancer Bladder
Colorectal cancer
Liver transplantation
Kidney transplantation

Prediction, early diagnosis, follow up of highly incident diseases in Egypt (chronic hepatitis C viral infection, hepatocellular carcinoma, renal diseases, cardiovascular complications of chronic kidney diseases, autoimmune diseases (Crohn’s and ulcerative colitis), cancer bladder, liver and kidney transplantation.

Role of genetic variants in pathophysiology of different diseases, studying their role in incidence, prediction, diagnosis and prognosis of diseases.

I- LIVER and GASTRO-INTESTINAL TRACT

Clinical Chemistry Department attempts to clarify the pathogenesis, helps in early prediction, diagnosis and prognosis of chronic liver diseases and GIT diseases. It can also guide therapeutic modalities in liver diseases. In HCC; our laboratory is trying to early detect HCC, spot metastasis, early detection of recurrence and monitoring therapeutic intervention.

II- KIDNEY AND UROGENITAL TRACT DISEASES

Clarification of the pathogenesis of renal and urogenital tract diseases and their early diagnosis and monitoring therapeutic modalities.

Structure

Laboratories and units under the umberella of the Clinical chemistry department

1- Main laboratory (Chemistry and Hormone Units)

** Outpatient laboratory undertaking the routine chemistry tests for the patients visiting different TBRI clinics daily; as well as the inpatients in the different clinical departments at the institute during morning and day hours.

2- Emergency laboratory

** Emergency laboratory for performance of analytical tests to critically ill patients admitted to the inpatients of clinical departments at the institute during mid and night shifts.

3- Research laboratory

** Research laboratory for performing the researches in the different fields of Clinical Chemistry with special attention to hepatic, gastrointestinal, renal and urological diseases together with their associated cardiovascular complications and genetic polymorphisms, which are the main concern of the research strategy of Theodor Bilharz Research Institute (TBRI).

Staff working in the Clinical chemistry department

Head of the department

(8) Emeritus Professors

(10) Researchers

(2) Assistant researchers

(1) Doctor resident

(4) Nurses

(10) Laboratory technicians

(3) Secretarial staff

Techniques

Our Clinical Chemistry Department elaborate techniques; including:

Automated auto-analyzers: two Beckman Coulters AU480 for routine laboratory work.
Point of care testing (POCT) for detection of cardiac biomarkers: CK-MB mass, d-Dimer and Troponin I.
Ion Selective Electrodes: estimation of potassium, sodium and chloride on I – lyte Instrumentational laboratory devices.
Potentiometric analysis: estimation of PH, ionized calcium, bicarbonate, CO2, PO2, chloride, potassium and sodium on Gem Premier 3000 machine.
Chemiluminescence for performance of hormones, tumor markers and drug levels on Siemens Advia Centaur CP instrument.
ELISA for performance of research analytes.

Work In Progress

For the routine work of the Clinical Chemistry department:

1- Renewal project of the laboratory infrastructure.

2- One of our department priorities is providing high quality laboratory services, so we are planning to be accredited with ISO 15189 certificate and GAHAR accreditation.

For the research work in the Clinical Chemistry department:

Ongoing research projects in the department

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Services

Our Clinical Chemistry department combines modern automation with the personal skills of a dedicated team of pathologists, clinical chemists, and technologists. We provide a range of services, including routine testing, stat testing, point-of-care testing, and specialized tests, and report critical values to providers 24 hours a day, seven days a week.

Specialization:
The assay of various chemical constituents in blood, urine, other biological fluids or tissues that help in the clarification of the abnormal metabolic processes which underlie symptoms of the diseases, thus helping prediction, early diagnosis, follow up, management and prognosis.

Scientific and technological experience:
The staff members experience the performance of different analytical techniques applied in the clinical chemistry department.

Performance of hepatic function panel, renal function panel, cardiac enzymes, blood gas analysis, blood glucose, thyroid panel, lipid panel and tumor markers.

Training

Training of students, laboratory personnels, medical and paramedical staff for all laboratory techniques.

Training courses prepared and presented by the department

Laboratory errors and quality control; the course implied the following: Basic laboratory principles, types of laboratory errors, quality control, quality assurance and quality improvement: Concepts and implementations.
Instruments of Clinical Chemistry laboratory
Blood sampling and preanalytical variables affecting sampling quality
Blood sampling and centrifugation
Highlights on Molecular techniques and applications in clinical chemistry department
Quality practice and ethics in scientific research studies

Publications

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Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,

Projects

Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s,